Insulin-Sensitizers, Polycystic Ovary Syndrome and Gynaecological Cancer Risk
نویسندگان
چکیده
منابع مشابه
Insulin-Sensitizers, Polycystic Ovary Syndrome and Gynaecological Cancer Risk
Preclinical, early phase clinical trials and epidemiological evidence support the potential role of insulin-sensitizers in cancer prevention and treatment. Insulin-sensitizers improve the metabolic and hormonal profile in PCOS patients and may also act as anticancer agents, especially in cancers associated with hyperinsulinemia and oestrogen dependent cancers. Several lines of evidence support ...
متن کاملThe effects of insulin sensitizers on the cardiovascular risk factors in women with polycystic ovary syndrome.
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in pre-menopausal women characterized by menstrual cycle disturbances, chronic anovulation, and clinical and/or biochemical hyperandrogenism. Although, the primary etiology of PCOS remains unknown, insulin resistance/hyperinsulinemia plays a pivotal role in the pathogenesis of the syndrome. A growing body of recent data supp...
متن کاملPolycystic ovary syndrome and epilepsy—a gynaecological perspective
The prevalence of polycystic ovaries (PCO) and polycystic ovary syndrome (PCOS) in the general population is approximately 20 and 10%, respectively, and published studies suggest a similar prevalence in women with epilepsy. These data do not suggest that epilepsy is associated with a higher prevalence of the condition, and it would appear that the background prevalence of PCO and PCOS is the sa...
متن کامل[Use of insulin sensitizers in the treatment of infertility in patients with polycystic ovary syndrome (POS)].
A síndrome dos ovários policísticos (SOP) é uma condição heterogênea, que apresenta grande variedade de sintomas clínicos e alterações endócrinas e metabólicas. É a mais frequente endocrinopatia da população feminina jovem. Afeta cerca de 5–10% das mulheres em idade reprodutiva, sendo a maior causa de infertilidade nas pacientes anovuladoras. Seu tratamento é baseado na sintomatologia preponder...
متن کاملInsulin Resistance and Polycystic Ovary Syndrome.
BACKGROUND Insulin resistance and the associated compensatory hyperinsulinemia are common findings in women with PCOS, and may play a key role in this condition. METHODS In this article, we focused on the significance of insulin resistance in PCOS, reviewing the available literature on epidemiology, pathogenesis, pathophysiology and treatment of this condition. RESULTS It has been estimated...
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ژورنال
عنوان ژورنال: International Journal of Endocrinology
سال: 2016
ISSN: 1687-8337,1687-8345
DOI: 10.1155/2016/8671762